Combined Array Comparative Genomic Hybridization and Tissue Microarray Analysis Suggest PAK1 at 11q13.5-q14 as a Critical Oncogene Target in Ovarian Carcinoma

Amplification of chromosomal regions leads to an increase of DNA copy numbers and expression of oncogenes in many human tumors. The identification of tumor-specific oncogene targets has potential diagnostic and therapeutic implications. To identify distinct spectra of oncogenic alterations in ovaria...

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Autors principals: Schraml, Peter, Schwerdtfeger, Georg, Burkhalter, Felix, Raggi, Anna, Schmidt, Dietmar, Ruffalo, Teresa, King, Walter, Wilber, Kim, Mihatsch, Michael J., Moch, Holger
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2003
Matèries:
Regular Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868266/
https://ncbi.nlm.nih.gov/pubmed/12937139
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