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Down-Regulation of Nitric Oxide Synthase-2 and Cyclooxygenase-2 Pathways by p53 in Squamous Cell Carcinoma

The goal of this study was to analyze the correlation between inducible nitric oxide synthase (iNOS) and COX-2 activities and p53 gene status in head and neck squamous cell carcinomas (HNSCCs) in vivo and in vitro. In a series of 43 HNSCCs we observed an up-regulation of both iNOS and COX-2 pathways...

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Autors principals: Gallo, Oreste, Schiavone, Nicola, Papucci, Laura, Sardi, Iacopo, Magnelli, Lucia, Franchi, Alessandro, Masini, Emanuela, Capaccioli, Sergio
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868223/
https://ncbi.nlm.nih.gov/pubmed/12875991
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