One-Step Detection of c-kit Point Mutations Using Peptide Nucleic Acid-Mediated Polymerase Chain Reaction Clamping and Hybridization Probes

The prognostic significance of somatic activating codon 816 c-kit mutations in pediatric urticaria pigmentosa has not yet been established in detail. Detection of such mutations in archival paraffin-embedded biopsies is usually hampered by an abundance of surrounding normal cells. Here we describe a...

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Bibliographic Details
Main Authors: Sotlar, Karl, Escribano, Luis, Landt, Olfert, Möhrle, Stefanie, Herrero, Sonia, Torrelo, Antonio, Lass, Ulrich, Horny, Hans-Peter, Bültmann, Burkhard
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 2003
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Technical Advance
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868096/
https://ncbi.nlm.nih.gov/pubmed/12598308
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