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Isoform-Specific Potentiation of Stem and Progenitor Cell Engraftment by AML1/RUNX1
BACKGROUND: AML1/RUNX1 is the most frequently mutated gene in leukaemia and is central to the normal biology of hematopoietic stem and progenitor cells. However, the role of different AML1 isoforms within these primitive compartments is unclear. Here we investigate whether altering relative expressi...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1868041/ https://ncbi.nlm.nih.gov/pubmed/17503961 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0040172 |
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