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Molecular Mechanisms of the Diabetogenic Effects of Arsenic: Inhibition of Insulin Signaling by Arsenite and Methylarsonous Acid

BACKGROUND: Increased prevalences of diabetes mellitus have been reported among individuals chronically exposed to inorganic arsenic (iAs). However, the mechanisms underlying the diabetogenic effects of iAs have not been characterized. We have previously shown that trivalent metabolites of iAs, arse...

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Detalhes bibliográficos
Main Authors: Paul, David S., Harmon, Anne W., Devesa, Vicenta, Thomas, David J., Stýblo, Miroslav
Formato: Artigo
Idioma:Inglês
Publicado em: National Institute of Environmental Health Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867998/
https://ncbi.nlm.nih.gov/pubmed/17520061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.9867
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