Atrazine-Induced Aromatase Expression Is SF-1 Dependent: Implications for Endocrine Disruption in Wildlife and Reproductive Cancers in Humans

BACKGROUND: Atrazine is a potent endocrine disruptor that increases aromatase expression in some human cancer cell lines. The mechanism involves the inhibition of phosphodiesterase and subsequent elevation of cAMP. METHODS: We compared steroidogenic factor 1 (SF-1) expression in atrazine responsive...

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Autors principals: Fan, WuQiang, Yanase, Toshihiko, Morinaga, Hidetaka, Gondo, Shigeki, Okabe, Taijiro, Nomura, Masatoshi, Komatsu, Tomoko, Morohashi, Ken-Ichirou, Hayes, Tyrone B., Takayanagi, Ryoichi, Nawata, Hajime
Format: Artigo
Idioma:Inglês
Publicat: National Institute of Environmental Health Sciences 2007
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867956/
https://ncbi.nlm.nih.gov/pubmed/17520059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.9758
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