Transgenic Expression of Ad4BP/SF-1 in Fetal Adrenal Progenitor Cells Leads to Ectopic Adrenal Formation

Deficiency of adrenal 4 binding protein/steroidogenic factor 1 (Ad4BP/SF-1; NR5A1) impairs adrenal development in a dose-dependent manner, whereas overexpression of Ad4BP/SF-1 is associated with adrenocortical tumorigenesis. Despite its essential roles in adrenal development, the mechanism(s) by whi...

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Hlavní autoři: Zubair, Mohamad, Oka, Sanae, Parker, Keith L., Morohashi, Ken-ichirou
Médium: Artigo
Jazyk:Inglês
Vydáno: The Endocrine Society 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818689/
https://ncbi.nlm.nih.gov/pubmed/19628584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2009-0055
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