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Mass Spectrometry-Based Loss of Heterozygosity Analysis of Single-Nucleotide Polymorphism Loci in Paraffin Embedded Tumors Using the MassEXTEND Assay : Single-Nucleotide Polymorphism Loss of Heterozygosity Analysis of the Protein Tyrosine Phosphatase Receptor Type J in Familial Colorectal Cancer

As the number of identified single-nucleotide polymorphisms (SNPs) increases, high-throughput methods are required to characterize the informative loci in large patient series. We investigated the feasibility of MassEXTEND LOH analysis using Sequenom’s MassArray RT software, a mass spectrometry meth...

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Main Authors: van Puijenbroek, Marjo, Dierssen, Jan Willem F., Stanssens, Patrick, van Eijk, Ronald, Marie Cleton-Jansen, Anne, van Wezel, Tom, Morreau, Hans
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867548/
https://ncbi.nlm.nih.gov/pubmed/16258161
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