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Rapid Polymerase Chain Reaction-Based Detection of Epidermal Growth Factor Receptor Gene Mutations in Lung Adenocarcinomas

Somatic mutations in the tyrosine kinase domain of the epidermal growth factor receptor (EGFR) gene are present in lung adenocarcinomas that respond to the EGFR inhibitors gefitinib and erlotinib. Two types of mutations account for ∼90% of mutated cases: short in-frame deletions in exon 19 and a spe...

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Detalhes bibliográficos
Main Authors: Pan, Qiulu, Pao, William, Ladanyi, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867537/
https://ncbi.nlm.nih.gov/pubmed/16049312
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