Challenges and Pitfalls in HNPCC Screening by Microsatellite Analysis and Immunohistochemistry

Hereditary non-polyposis colorectal cancer (HNPCC) accounts for approximately 2 to 4% of the total colorectal cancer burden. For economic reasons a diagnostic “stepladder” is recommended. After evaluation of the family history, diagnostic microsatellite instability (MSI) analysis has found its place...

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Main Authors: Müller, Annegret, Giuffre, Giuseppe, Edmonston, Tina Bocker, Mathiak, Micaela, Roggendorf, Beate, Heinmöller, Ernst, Brodegger, Thomas, Tuccari, Giovanni, Mangold, Elisabeth, Buettner, Reinhard, Rüschoff, Josef
格式: Artigo
語言:Inglês
出版: American Society for Investigative Pathology 2004
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867493/
https://ncbi.nlm.nih.gov/pubmed/15507669
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