Analysis of HER2 Gene Amplification Using an Automated Fluorescence in Situ Hybridization Signal Enumeration System

The HER2 gene, amplified in 10 to 35% of invasive human breast carcinomas, has prognostic and therapeutic implications. Fluorescent in situ hybridization is one method currently used for assessing HER2 status, but fluorescent in situ hybridization involves the time-consuming step of manual signal en...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Stevens, Rachel, Almanaseer, Imad, Gonzalez, Miguel, Caglar, Derin, Knudson, Ryan A., Ketterling, Rhett P., Schrock, Daniel S., Seemayer, Thomas A., Bridge, Julia A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2007
Schlagworte:
Technical Advance
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867448/
https://ncbi.nlm.nih.gov/pubmed/17384205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/jmoldx.2007.060102
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