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Enteric Expression of the Integrin α(v)β(6) Is Essential for Nematode-Induced Mucosal Mast Cell Hyperplasia and Expression of the Granule Chymase, Mouse Mast Cell Protease-1
The immunoregulatory cytokine transforming growth factor (TGF)-β(1) is secreted as a biologically inactive complex with latency-associated peptide, which must be modified by local factors to expose the functionally active cytokine. The epithelial integrin α(v)β(6) mediates local activation of TGF-β(...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society for Investigative Pathology
2002
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1867270/ https://ncbi.nlm.nih.gov/pubmed/12213704 |
| Ετικέτες: |
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