Multiple Head and Neck Tumors Frequently Originate from a Single Preneoplastic Lesion

The development of second primary tumors has a negative impact on the prognosis of head and neck squamous cell carcinoma. Previously, we detected genetically altered and tumor-related mucosal lesions in the resection margins in 25% of unselected head and neck squamous cell carcinoma patients (Tabor...

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Main Authors: Tabor, Maarten P., Brakenhoff, Ruud H., Ruijter-Schippers, Henrique J., van der Wal, Jacqueline E., Snow, Gordon B., Leemans, C. René, Braakhuis, Boudewijn J. M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 2002
Fag:
Regular Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867244/
https://ncbi.nlm.nih.gov/pubmed/12213734
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