Functional Tyrosine Kinase Inhibitor Profiling : A Generally Applicable Method Points to a Novel Role of Platelet-Derived Growth Factor Receptor-β in Tuberous Sclerosis

Tumors often exhibit activation of specific tyrosine kinases, which may allow targeting of therapy through inhibition of tyrosine kinase signaling. This strategy has been used successfully in the development of STI571 (gleevec), an inhibitor of bcr-abl tyrosine kinase that has been used successfully...

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Библиографические подробности
Главные авторы: Arbiser, Jack L., Govindarajan, Baskaran, Bai, Xianhe, Onda, Hiroaki, Kazlauskas, Andrius, Lim, So Dug, Amin, Mahul B., Claesson-Welsh, Lena
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Investigative Pathology 2002
Предметы:
Technical Advance
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867243/
https://ncbi.nlm.nih.gov/pubmed/12213705
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