PolyA Deletions in Hereditary Nonpolyposis Colorectal Cancer : Mutations Before a Gatekeeper

Microsatellite instability (MSI) secondary to loss of DNA mismatch repair (MMR) is present in adenomas and colorectal carcinomas from individuals with hereditary nonpolyposis colorectal cancer (HNPCC). To better characterize when MMR loss occurs during HNPCC progression, the extent of deletions in n...

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Hlavní autoři: Kim, Kyoung-Mee, Salovaara, Reijo, Mecklin, Jukka-Pekka, Järvinen, Heikki J., Aaltonen, Lauri A., Shibata, Darryl
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2002
Témata:
Regular Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867223/
https://ncbi.nlm.nih.gov/pubmed/11943734
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