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The Complexity of KIT Gene Mutations and Chromosome Rearrangements and Their Clinical Correlation in Gastrointestinal Stromal (Pacemaker Cell) Tumors

Gastrointestinal stromal (pacemaker cell) tumors (GIST/GIPACTs) are frequently associated with activating KIT mutations, primarily of exon 11 and rarely of exons 9 and 13, as well as certain chromosome rearrangements. Reports regarding the frequency and prognostic significance of KIT mutations are c...

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Detalhes bibliográficos
Main Authors: Andersson, Johanna, Sjögren, Helene, Meis-Kindblom, Jeanne M., Stenman, Göran, Åman, Pierre, Kindblom, Lars-Gunnar
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867112/
https://ncbi.nlm.nih.gov/pubmed/11786393
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