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Immunophenotypic Analysis of the TCR-Vβ Repertoire in 98 Persistent Expansions of CD3(+)/TCR-αβ(+) Large Granular Lymphocytes : Utility in Assessing Clonality and Insights into the Pathogenesis of the Disease

At present, a major challenge in the initial diagnosis of leukemia of large granular lymphocytes (LGLs) is to establish the clonal nature of the expanded population. In the present study we have analyzed by flow cytometry immunophenotyping the TCR-Vβ repertoire of 98 consecutive cases of persistent...

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Detalhes bibliográficos
Main Authors: Lima, Margarida, Almeida, Julia, Santos, Ana Helena, dos Anjos Teixeira, Maria, del Carmen Alguero, Maria, Queirós, Maria Luís, Balanzategui, Ana, Justiça, Benvindo, Gonzalez, Marcos, San Miguel, Jesús F., Orfão, Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867049/
https://ncbi.nlm.nih.gov/pubmed/11696446
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