Immunophenotypic Analysis of the TCR-Vβ Repertoire in 98 Persistent Expansions of CD3(+)/TCR-αβ(+) Large Granular Lymphocytes : Utility in Assessing Clonality and Insights into the Pathogenesis of the Disease

At present, a major challenge in the initial diagnosis of leukemia of large granular lymphocytes (LGLs) is to establish the clonal nature of the expanded population. In the present study we have analyzed by flow cytometry immunophenotyping the TCR-Vβ repertoire of 98 consecutive cases of persistent...

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Hlavní autoři: Lima, Margarida, Almeida, Julia, Santos, Ana Helena, dos Anjos Teixeira, Maria, del Carmen Alguero, Maria, Queirós, Maria Luís, Balanzategui, Ana, Justiça, Benvindo, Gonzalez, Marcos, San Miguel, Jesús F., Orfão, Alberto
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2001
Témata:
Regular Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867049/
https://ncbi.nlm.nih.gov/pubmed/11696446
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