Anoxia-Induced Up-Regulation of Interleukin-8 in Human Malignant Melanoma : A Potential Mechanism for High Tumor Aggressiveness

Besides its proinflammatory properties, interleukin-8 (IL-8) has been suggested as an important promoter for melanoma growth. To study the role of IL-8 in melanoma biology, we determined the in vivo expression of IL-8 mRNA by in situ hybridization in primary melanoma lesions and metastases. High lev...

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Detalhes bibliográficos
Main Authors: Kunz, Manfred, Hartmann, Anke, Flory, Egbert, Toksoy, Atiye, Koczan, Dirk, Thiesen, Hans-Jürgen, Mukaida, Nafoumi, Neumann, Manfred, Rapp, Ulf Rüdiger, Bröcker, Eva-Bettina, Gillitzer, Reinhard
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 1999
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866897/
https://ncbi.nlm.nih.gov/pubmed/10487833
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