Hypoxia/reoxygenation induction of monocyte chemoattractant protein-1 in melanoma cells: involvement of nuclear factor-kappaB, stimulatory protein-1 transcription factors and mitogen-activated protein kinase pathways.

Monocyte chemoattractant protein-1 (MCP-1) expression is found in malignant melanoma and melanoma metastases. Since areas of hypoxia/reoxygenation (H/R) are a common feature of malignant tumours and metastases, we addressed the question whether melanoma cells produce MCP-1 upon exposure to H/R. In t...

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Bibliographische Detailangaben
Hauptverfasser: Kunz, Manfred, Bloss, Gisela, Gillitzer, Reinhard, Gross, Gerd, Goebeler, Matthias, Rapp, Ulf R, Ludwig, Stephan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2002
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222766/
https://ncbi.nlm.nih.gov/pubmed/12020348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20011749
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