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Molecular Genetic Analysis of Ependymal Tumors : NF2 Mutations and Chromosome 22q Loss Occur Preferentially in Intramedullary Spinal Ependymomas

Ependymal tumors are heterogeneous with regard to morphology, localization, age at first clinical manifestation, and prognosis. Several molecular alterations have been reported in these tumors, including allelic losses on chromosomes 10, 17, and 22 and mutations in the NF2 gene. However, in contrast...

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Hlavní autoři: Ebert, Christian, von Haken, Markus, Meyer-Puttlitz, Birgit, Wiestler, Otmar D., Reifenberger, Guido, Pietsch, Torsten, von Deimling, Andreas
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 1999
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866851/
https://ncbi.nlm.nih.gov/pubmed/10433955
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