Distinct Selectin Ligands on Colon Carcinoma Mucins Can Mediate Pathological Interactions among Platelets, Leukocytes, and Endothelium

Selectins are adhesion molecules that mediate calcium-dependent cell-cell interactions among leukocytes, platelets, and endothelial cells. The naturally occurring vascular ligands for the selectins are mostly mucin-type glycoproteins. Increased expression and altered glycosylation of mucins are know...

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Bibliographic Details
Main Authors: Kim, Young J., Borsig, Lubor, Han, Hui-Ling, Varki, Nissi M., Varki, Ajit
Format: Artigo
Language:Inglês
Published: American Society for Investigative Pathology 1999
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866847/
https://ncbi.nlm.nih.gov/pubmed/10433939
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