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A new family-based association test via a least-squares method

To test the association between a dichotomous phenotype and genetic marker based on family data, we propose a least-squares method using the vector of phenotypes and their cross products within each family. This new approach allows covariate adjustment and is numerically much simpler to implement co...

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書目詳細資料
Main Authors: Yang, Song, Joo, Jungnam, Feng, Ziding, Lin, Jing-Ping
格式: Artigo
語言:Inglês
出版: BioMed Central 2005
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866828/
https://ncbi.nlm.nih.gov/pubmed/16451567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-6-S1-S110
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