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A new family-based association test via a least-squares method
To test the association between a dichotomous phenotype and genetic marker based on family data, we propose a least-squares method using the vector of phenotypes and their cross products within each family. This new approach allows covariate adjustment and is numerically much simpler to implement co...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1866828/ https://ncbi.nlm.nih.gov/pubmed/16451567 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-6-S1-S110 |
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