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Construction of endophenotypes for complex diseases in the presence of heterogeneity

Endophenotypes such as behavior disorders have been increasingly adopted in genetic studies for complex traits. For efficient gene mapping, it is essential that an endophenotype is associated with the disease of interest and is inheritable or co-segregating within families. In this study, we propose...

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Detalhes bibliográficos
Main Authors: Chen, Chien-Hsiun, Kuo, Chih-Ling, Lin, Michael CP, Liang, Yu-Jen, Fann, Cathy SJ
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866797/
https://ncbi.nlm.nih.gov/pubmed/16451598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-6-S1-S139
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