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Construction of endophenotypes for complex diseases in the presence of heterogeneity

Endophenotypes such as behavior disorders have been increasingly adopted in genetic studies for complex traits. For efficient gene mapping, it is essential that an endophenotype is associated with the disease of interest and is inheritable or co-segregating within families. In this study, we propose...

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Hlavní autoři: Chen, Chien-Hsiun, Kuo, Chih-Ling, Lin, Michael CP, Liang, Yu-Jen, Fann, Cathy SJ
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866797/
https://ncbi.nlm.nih.gov/pubmed/16451598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-6-S1-S139
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