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Analysis of alcohol dependence phenotype in the COGA families using covariates to detect linkage

Linkage analysis methods that incorporate etiological heterogeneity of complex diseases are likely to demonstrate greater power than traditional linkage analysis methods. Several such methods use covariates to discriminate between linked and unlinked pedigrees with respect to a certain disease locus...

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Hlavní autoři: Reck, Brian H, Mukhopadhyay, Nandita, Tsai, Hui-Ju, Weeks, Daniel E
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866792/
https://ncbi.nlm.nih.gov/pubmed/16451603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-6-S1-S143
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