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Dopaminergic Mutations: Within-Family Association and Linkage in Multiplex Alcohol Dependence Families

Animal and human studies of addiction indicate that the D2 dopamine receptor (DRD2) plays a critical role in the mechanism of drug reward. D2 receptor density in the brains of alcoholics has been shown to be reduced relative to controls. Previous studies of DRD2 in association with alcohol dependenc...

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Detalhes bibliográficos
Main Authors: Hill, Shirley Y., Hoffman, Eric K., Zezza, Nicholas, Thalamuthu, Anbupalam, Weeks, Daniel E., Matthews, Abigail G., Mukhopadhyay, Indranil
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3280909/
https://ncbi.nlm.nih.gov/pubmed/17948902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.b.30630
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