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Multifactor-dimensionality reduction versus family-based association tests in detecting susceptibility loci in discordant sib-pair studies

Complex diseases are generally thought to be under the influence of multiple, and possibly interacting, genes. Many association methods have been developed to identify susceptibility genes assuming a single-gene disease model, referred to as single-locus methods. Multilocus methods consider joint ef...

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Bibliografiset tiedot
Päätekijät: Meng, Yan, Ma, Qianli, Yu, Yi, Farrell, John, Farrer, Lindsay A, Wilcox, Marsha A
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2005
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866789/
https://ncbi.nlm.nih.gov/pubmed/16451606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-6-S1-S146
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