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Inclusion of unaffected sibs increases power in model-free linkage analysis of a behavioral trait

Study design strategies are of critical importance in the search for genes underlying complex diseases. Two important design choices in planning gene mapping studies are the analytic strategy to be used, which will have an impact on the type of data to be collected, and the choice of genetic markers...

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Detalles Bibliográficos
Main Authors: Plancoulaine, Sabine, Alcaïs, Alexandre, Chen, Yue, Abel, Laurent, Gagnon, France
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866764/
https://ncbi.nlm.nih.gov/pubmed/16451631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-6-S1-S22
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