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Critical values and variation in type I error along chromosomes in the COGA dataset using the applied pseudo-trait method

BACKGROUND: By analyzing a "pseudo-trait," a trait not linked or associated with any of the markers tested, the distribution of the test statistic under the null hypothesis can provide the critical value for the appropriate percentile of the distribution. In addition, the anecdotal observa...

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Main Authors: Papanicolaou, George J, Justice, Cristina M, Kovac, Illija M, Sorant, Alexa JM, Wilson, Alexander F
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866729/
https://ncbi.nlm.nih.gov/pubmed/16451666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-6-S1-S54
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