Biochemical Detection of Novel Anaplastic Lymphoma Kinase Proteins in Tissue Sections of Anaplastic Large Cell Lymphoma

The (2;5) translocation, found in many T-cell and null cell anaplastic large cell lymphomas (ALCLs), creates a hybrid gene encoding the 80-kd NPM-ALK protein. Typically neoplastic cells show labeling of both nucleus and cytoplasm for anaplastic lymphoma kinase (ALK) and for the N-terminus of nucleop...

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Main Authors: Pulford, Karen, Falini, Brunangelo, Cordell, Jaqueline, Rosenwald, Andreas, Ott, German, Müller-Hermelink, Hans-Konrad, MacLennan, Kenneth A., Lamant, Laurence, Carbone, Antonio, Campo, Elias, Mason, David Y.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Investigative Pathology 1999
Fag:
Short Communication
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866626/
https://ncbi.nlm.nih.gov/pubmed/10362790
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