Diversity of Genomic Breakpoints in TFG-ALK Translocations in Anaplastic Large Cell Lymphomas : Identification of a New TFG-ALK(XL) Chimeric Gene with Transforming Activity

Anaplastic large cell lymphomas are associated with chromosomal aberrations involving the anaplastic lymphoma kinase (ALK) gene at 2p23 that result in the expression of novel chimeric ALK proteins with transforming properties. In most of these tumors, the t(2;5)(p23;q35) generates the NPM-ALK fusion...

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Detalhes bibliográficos
Main Authors: Hernández, Luis, Beà, Sílvia, Bellosillo, Beatriz, Pinyol, Magda, Falini, Brunangelo, Carbone, Antonino, Ott, German, Rosenwald, Andreas, Fernández, Alberto, Pulford, Karen, Mason, David, Morris, Stephan W., Santos, Eugenio, Campo, Elias
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2002
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867210/
https://ncbi.nlm.nih.gov/pubmed/11943732
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