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Diversity of Genomic Breakpoints in TFG-ALK Translocations in Anaplastic Large Cell Lymphomas : Identification of a New TFG-ALK(XL) Chimeric Gene with Transforming Activity

Anaplastic large cell lymphomas are associated with chromosomal aberrations involving the anaplastic lymphoma kinase (ALK) gene at 2p23 that result in the expression of novel chimeric ALK proteins with transforming properties. In most of these tumors, the t(2;5)(p23;q35) generates the NPM-ALK fusion...

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Hlavní autoři: Hernández, Luis, Beà, Sílvia, Bellosillo, Beatriz, Pinyol, Magda, Falini, Brunangelo, Carbone, Antonino, Ott, German, Rosenwald, Andreas, Fernández, Alberto, Pulford, Karen, Mason, David, Morris, Stephan W., Santos, Eugenio, Campo, Elias
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2002
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867210/
https://ncbi.nlm.nih.gov/pubmed/11943732
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