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A statistical method for adjusting covariates in linkage analysis with sib pairs

BACKGROUND: We propose a statistical method that includes the use of longitudinal regression models and estimation procedures for adjusting for covariate effects in applying the Haseman-Elston (HE) method for linkage analysis. Our methodology, which uses the covariate adjusted trait, contains three...

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Hlavní autoři: Wu, Colin O, Zheng, Gang, Leifer, Eric, Follmann, Dean, Lin, Jing-Ping
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866488/
https://ncbi.nlm.nih.gov/pubmed/14975119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-4-S1-S51
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