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Comparison of longitudinal variance components and regression-based approaches for linkage detection on chromosome 17 for systolic blood pressure

We compare two methods to detect genetic linkage by using serial observations of systolic blood pressure in pedigree data from the Framingham Heart Study focusing on chromosome 17. The first method is a variance components (VC) approach that incorporates longitudinal pedigree data, and the second me...

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Hlavní autoři: Andrade, Mariza de, Olswold, Curtis
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866451/
https://ncbi.nlm.nih.gov/pubmed/14975085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-4-S1-S17
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