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Comparison of longitudinal variance components and regression-based approaches for linkage detection on chromosome 17 for systolic blood pressure
We compare two methods to detect genetic linkage by using serial observations of systolic blood pressure in pedigree data from the Framingham Heart Study focusing on chromosome 17. The first method is a variance components (VC) approach that incorporates longitudinal pedigree data, and the second me...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2003
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1866451/ https://ncbi.nlm.nih.gov/pubmed/14975085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-4-S1-S17 |
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