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Computation-Based Discovery of Related Transcriptional Regulatory Modules and Motifs Using an Experimentally Validated Combinatorial Model

Gene expression is regulated by transcription factors that interact with cis-regulatory elements. Predicting these elements from sequence data has proven difficult. We describe here a successful computational search for elements that direct expression in a particular temporal-spatial pattern in the...

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Detalhes bibliográficos
Main Authors: Halfon, Marc S., Grad, Yonatan, Church, George M., Michelson, Alan M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC186630/
https://ncbi.nlm.nih.gov/pubmed/12097338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.228902
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