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Purification method directly impacts effectiveness of an EGF-coupled targeting agent for noninvasive tumor detection in mice

Receptor targeting is an effective method of enhancing fluorescence signal in tumors for optical imaging. We previously used EGF conjugated to IRDye® 800CW to detect and track orthotopic prostate tumors in mice. In this study, our goal was to identify a reliable assay for targeting agent integrity i...

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Detalhes bibliográficos
Main Authors: Kovar, Joy L., Volcheck, William M., Chen, Jiyan, Simpson, Melanie A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866276/
https://ncbi.nlm.nih.gov/pubmed/17188228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2006.11.021
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