Bovine Viral Diarrhea Virus: Prevention of Persistent Fetal Infection by a Combination of Two Mutations Affecting E(rns) RNase and N(pro) Protease

Different genetically engineered mutants of bovine viral diarrhea virus (BVDV) were analyzed for the ability to establish infection in the fetuses of pregnant heifers. The virus mutants exhibited either a deletion of the overwhelming part of the genomic region coding for the N-terminal protease N(pr...

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Detalhes bibliográficos
Main Authors: Meyers, Gregor, Ege, Andreas, Fetzer, Christiane, von Freyburg, Martina, Elbers, Knut, Carr, Veronica, Prentice, Helen, Charleston, Bryan, Schürmann, Eva-Maria
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866084/
https://ncbi.nlm.nih.gov/pubmed/17215285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02372-06
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