In Vitro Study of the Effects of Precore and Lamivudine-Resistant Mutations on Hepatitis B Virus Replication

Understanding the consequences of mutation in the hepatitis B virus (HBV) genome on HBV replication is critical for treating chronic HBV infection. In this study, HBV replication in HepG2 cells initiated by transduction with precore (PC), rtM204I, and wild-type (wt) HBV recombinant baculoviruses was...

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Detalhes bibliográficos
Main Authors: Heipertz, Richard A., Miller, Thomas G., Kelley, Colleen M., Delaney, William E., Locarnini, Stephen A., Isom, Harriet C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866076/
https://ncbi.nlm.nih.gov/pubmed/17215289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02341-06
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