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Frequency and Phenotype of JC Virus-Specific CD8(+) T Lymphocytes in the Peripheral Blood of Patients with Progressive Multifocal Leukoencephalopathy

JC virus (JCV)-specific CD8(+) cytotoxic T lymphocytes (CTL) are associated with a favorable outcome in patients with progressive multifocal leukoencephalopathy (PML) and cross-recognize the polyomavirus BK virus (BKV). We sought to determine the frequency and phenotype in fresh blood of CD8(+) T ce...

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Autors principals: Lima, Marco A., Marzocchetti, Angela, Autissier, Patrick, Tompkins, Troy, Chen, Yiping, Gordon, Jennifer, Clifford, David B., Gandhi, Rajesh T., Venna, Nagagopal, Berger, Joseph R., Koralnik, Igor J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866063/
https://ncbi.nlm.nih.gov/pubmed/17229701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01809-06
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