Efficient in vitro Expansion of JC virus-Specific CD8(+) T-Cell Responses by JCV peptide-stimulated Dendritic Cells from patients with Progressive Multifocal Leukoencephalopathy

Progressive multifocal leukoencephalopathy (PML) is a demyelinating disease of the brain caused by JC virus (JCV) for which there is no cure. PML patients who have JCV-specific CD8(+) cytotoxic T lymphocytes (CTL) in their blood have a better clinical outcome. We compared JCV-specific CTL responses...

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Détails bibliographiques
Auteurs principaux: Marzocchetti, Angela, Lima, Marco, Tompkins, Troy, Kavanagh, Daniel.G., Gandhi, Rajesh T., O'Neill, David W., Bhardwaj, Nina, Koralnik, Igor J.
Format: Artigo
Langue:Inglês
Publié: 2008
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2692892/
https://ncbi.nlm.nih.gov/pubmed/19062062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2008.10.046
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