Contrasting Effects of Human, Canine, and Hybrid Adenovirus Vectors on the Phenotypical and Functional Maturation of Human Dendritic Cells: Implications for Clinical Efficacy

Antipathogen immune responses create a balance between immunity, tolerance, and immune evasion. However, during gene therapy most viral vectors are delivered in substantial doses and are incapable of expressing gene products that reduce the host's ability to detect transduced cells. Gene transf...

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Bibliographic Details
Main Authors: Perreau, Matthieu, Mennechet, Franck, Serratrice, Nicolas, Glasgow, Joel N., Curiel, David T., Wodrich, Harald, Kremer, Eric J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2007
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1866049/
https://ncbi.nlm.nih.gov/pubmed/17229706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01530-06
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