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Tropism Modification of Adenovirus Vectors by Peptide Ligand Insertion into Various Positions of the Adenovirus Serotype 41 Short-Fiber Knob Domain

Recombinant adenoviruses have emerged as promising agents in therapeutic gene transfer, genetic vaccination, and viral oncolysis. Therapeutic applications of adenoviruses, however, would benefit substantially from targeted virus cell entry, for example, into cancer or immune cells, as opposed to the...

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Detalhes bibliográficos
Main Authors: Hesse, Andrea, Kosmides, Daniela, Kontermann, Roland E., Nettelbeck, Dirk M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865974/
https://ncbi.nlm.nih.gov/pubmed/17192304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02722-06
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