Inhibition of Filovirus Replication by the Zinc Finger Antiviral Protein

The zinc finger antiviral protein (ZAP) was recently shown to inhibit Moloney murine leukemia virus and Sindbis virus replication. We tested whether ZAP also acts against Ebola virus (EBOV) and Marburg virus (MARV). Antiviral effects were observed after infection of cells expressing the N-terminal p...

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Bibliographic Details
Main Authors: Müller, Stefanie, Möller, Peggy, Bick, Matthew J., Wurr, Stephanie, Becker, Stephan, Günther, Stephan, Kümmerer, Beate M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2007
Subjects:
Genome Replication and Regulation of Viral Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865956/
https://ncbi.nlm.nih.gov/pubmed/17182693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01601-06
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