Nativelike topology assembly of small proteins using predicted restraints in Monte Carlo folding simulations

By incorporating predicted secondary and tertiary restraints derived from multiple sequence alignments into ab initio folding simulations, it has been possible to assemble native-like tertiary structures for a test set of 19 nonhomologous proteins ranging from 29 to 100 residues in length and repres...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Ortiz, Angel R., Kolinski, Andrzej, Skolnick, Jeffrey
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1998
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18658/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9448278/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.3.1020
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