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The ChrA-ChrS and HrrA-HrrS Signal Transduction Systems Are Required for Activation of the hmuO Promoter and Repression of the hemA Promoter in Corynebacterium diphtheriae

Transcription of the Corynebacterium diphtheriae hmuO gene, which encodes a heme oxygenase involved in heme iron utilization, is activated in a heme- or hemoglobin-dependent manner in part by the two-component system ChrA-ChrS. Mutation of either the chrA or the chrS gene resulted in a marked reduct...

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Autors principals: Bibb, Lori A., Kunkle, Carey A., Schmitt, Michael P.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865786/
https://ncbi.nlm.nih.gov/pubmed/17353293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01821-06
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