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CD4(+) CD25(+) Regulatory T Cells Suppress CD4(+) T-Cell Function and Inhibit the Development of Plasmodium berghei-Specific TH1 Responses Involved in Cerebral Malaria Pathogenesis

The infection of mice with Plasmodium berghei ANKA constitutes the best available mouse model for human Plasmodium falciparum-mediated cerebral malaria, a devastating neurological syndrome that kills nearly 2.5 million people every year. Experimental data suggest that cerebral disease results from t...

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Detalhes bibliográficos
Main Authors: Nie, Catherine Q., Bernard, Nicholas J., Schofield, Louis, Hansen, Diana S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865737/
https://ncbi.nlm.nih.gov/pubmed/17325053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01783-06
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