γδ T-Cell Function in Pathogenesis of Cerebral Malaria in Mice Infected with Plasmodium berghei ANKA

Mice depleted of γδ T cells by monoclonal antibody treatment and infected with Plasmodium berghei ANKA did not develop cerebral malaria (CM). In striking contrast, δ(0/0) mice infected with P. berghei developed CM despite their γδ T-cell deficiency. γδ T cells appear to be essential for the pathogen...

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Hauptverfasser: Yañez, D. M., Batchelder, J., van der Heyde, H. C., Manning, D. D., Weidanz, W. P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1999
Schlagworte:
Fungal and Parasitic Infections
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC96335/
https://ncbi.nlm.nih.gov/pubmed/9864254
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