Protective Meningococcal Capsular Polysaccharide Epitopes and the Role of O Acetylation

Previous studies with group C meningococcal polysaccharide-tetanus toxoid (GCMP-TT) conjugates had suggested that the GCMP O-acetyl group masked the protective epitope for group C meningococci through steric hindrance or altered conformations. For this report, we confirmed this phenomenon and perfor...

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Autores principales: Fusco, Peter C., Farley, Esmé K., Huang, Chun-Hsien, Moore, Samuel, Michon, Francis
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2007
Materias:
Vaccine Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865638/
https://ncbi.nlm.nih.gov/pubmed/17376859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00009-07
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