O-acetylation of typhoid capsular polysaccharide confers polysaccharide rigidity and immunodominance by masking additional epitopes

In this work, we explore the effects of O-acetylation on the physical and immunological characteristics of the WHO International Standards of Vi polysaccharide (Vi) from both Citrobacter freundii and Salmonella enterica serovar Typhi. We find that, although structurally identical according to NMR, t...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Vaccine
Egile Nagusiak: Hitri, Krisztina, Kuttel, Michelle M., De Benedetto, Gianluigi, Lockyer, Kay, Gao, Fang, Hansal, Peter, Rudd, Timothy R., Beamish, Emma, Rijpkema, Sjoerd, Ravenscroft, Neil, Bolgiano, Barbara
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier Science 2019
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6997886/
https://ncbi.nlm.nih.gov/pubmed/31160100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2019.05.050
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